Integrins and Their Ligands

Publisher Website
Google Scholar
Abstract
The interactions of cells with extracellular matrices is of fundamental importance in many biological processes such as embryological development would healing and the maintenance of tissue integrity. Cells adhere to the extracellular matrix via specific cell surface receptors, most of which belong to a family of structurally related glycoproteins called integrins (Hynes 1987; Ruoslahti 1987). Integrins are heterodimers composed of an α subunit noncovalently associated with a β subunit. Fourteen different a subunits and eight different β subunits have thus far been identified, forming 20 different heterodimeric complexes (Fig. 1).

This publication has 149 references indexed in Scilit: