Simultaneous Multiple Comparison Procedures in Psychiatric Research

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Abstract
Methods are presented for using linear contrasts to make inferences about differences between the means of several populations on continuous dependent variables. These methods control the experimentwise error rate (the probability of committing one or more type 1 errors in the set of decisions made within the experiment) for linear contrasts which compare some sub-sets of populations with others. Appropriate methods are outlined for testing contrasts which have been planned (i.e., specified independently of the data on which they are tested) and defined post hoc (i.e., after an inspection of the data). We show how these methods can be adapted to the analysis of data from factorial analysis of variance research designs.

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