Incidence of Cancer Among Persons With Schizophrenia and Their Relatives
Open Access
- 1 June 2001
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of General Psychiatry
- Vol. 58 (6) , 573-578
- https://doi.org/10.1001/archpsyc.58.6.573
Abstract
NUMEROUS reports have suggested that the rates of physical illness differ between patients with schizophrenia and the general population. Although most evidence must be regarded as anecdotal,%1 some observations deserve further study, among them a decreased incidence of lung cancer,%2,3 which is counterintuitive given the increased rate and intensity of smoking among individuals with schizophrenia.%4 In genetic terms, the hypothesis is attractive that a schizophrenia vulnerability gene would simultaneously decrease the risk of lung cancer, despite heavy exposure to the strongest known environmental risk factor: tobacco smoke.Keywords
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