.GAMMA.-Chloronorvaline, a leucine analog from Streptomyces.
- 1 January 1980
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 33 (11) , 1249-1255
- https://doi.org/10.7164/antibiotics.33.1249
Abstract
.gamma.-Chloronorvaline (AL-719) and .gamma.-hydroxynorvalinelactone (AL-719Y) were isolated from the culture broth of S. griseosporeus AL-719. Physico-chemical studies led to the structure elucidation of AL-719 and 719Y, with their respective configurations of (2S, 4S) and (2S, 4R). AL-710 shows antibacterial activity on a synthetic agar, especially against Pseudomonas aeruginosa, which was reversed by L-leucine. The producing strain AL-719 was characterized.This publication has 2 references indexed in Scilit:
- New Amino Acids from Streptomyces*Biochemistry, 1967
- THE STRUCTURAL BASES OF SOME AMINO ACID ANTAGONISTS AND THEIR MICROBIOLOGICAL PROPERTIESAnnals of the New York Academy of Sciences, 1950