Percutaneous absorption of I,3-bis (2-chloroethyl)-I-nitrosourea (BCNU, carmustine) in mycosis fungoides
- 1 July 1977
- journal article
- research article
- Published by Oxford University Press (OUP) in British Journal of Dermatology
- Vol. 97 (1) , 65-67
- https://doi.org/10.1111/j.1365-2133.1977.tb15429.x
Abstract
The total percutaneous absorption of I,3‐bis(2‐chloroethyl)‐i‐nitrosourea (BCNU, carmustine) in 5 patients with mycosis fungoides, based on the 5 day urinary excretion of 14C‐labelled BCNU, ranged from 5 to 28%. Absorption through diseased skin was greater than through uninvolved skin.This publication has 6 references indexed in Scilit:
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- Regional Variation in Percutaneous Penetration in ManArchives of environmental health, 1971
- Treatment of Advanced Hodgkin’s Disease with [1,3 Bis (2-Chloroethyl)-1-Nitrosourea] BCNUNew England Journal of Medicine, 1971
- Absorption of Some Organic Compounds Through the Skin in ManJournal of Investigative Dermatology, 1970
- The physiological disposition of the carcinostatic 1,3‐bis(2‐chloroethyU‐l‐nitrosourea (BCNU) in man and animalsClinical Pharmacology & Therapeutics, 1967
- THE EFFECT OF DMSO ON PERCUTANEOUS PENETRATION OF HYDROCORTISONE AND TESTOSTERONE IN MAN*Annals of the New York Academy of Sciences, 1967