A Hepatitis Virus Complicating Studies With Mouse Leukemia

Abstract
Hepatitis was frequently observed in strain BALB/c mice during the course of studies with the Moloney murine leukemia virus. A virus isolated from mice with hepatic disease was propagated and quantitatively assayed by methods in vitro. The properties of this agent, designated MHV-A59, were detailed, and a relationship to one member of the established mouse “hepatoencephalitis” group of viruses was ascertained.