Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis inApcminmice
Open Access
- 10 January 2006
- journal article
- fj express-summaries
- Published by Wiley in The FASEB Journal
- Vol. 20 (3) , 506-508
- https://doi.org/10.1096/fj.05-4785fje
Abstract
Sulforaphane (SFN) is an isothiocyanate from broccoli that induces phase 2 detoxification enzymes. We recently reported that SFN acts as a histone deacetylase (HDAC) inhibitor in human colon cancer c...Keywords
Funding Information
- National Institutes of Health (CA-90890, CA-65525, CA-80176, CA-100608, CA-107693)
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