Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis inApcminmice

Abstract
Sulforaphane (SFN) is an isothiocyanate from broccoli that induces phase 2 detoxification enzymes. We recently reported that SFN acts as a histone deacetylase (HDAC) inhibitor in human colon cancer c...
Funding Information
  • National Institutes of Health (CA-90890, CA-65525, CA-80176, CA-100608, CA-107693)