EVALUATION OF FENBENDAZOLE AS AN ANTHELMINTIC FOR GASTROINTESTINAL NEMATODES OF CATTLE

  • 1 January 1978
    • journal article
    • research article
    • Vol. 39  (6) , 1037-1038
Abstract
Calves naturally infected with Ostertagia, Haemonchus, Trichostrongylus and Cooperia were used in a controlled experiment to determine the anthelmintic efficacy of fenbendazole, methyl-5-(phenylthio)-2-benzimidazolecarbamate, and to compare this with the efficacy of levamisole. The calves were placed in dry lots for approximately 3 wk, ensuring that immature Ostertagia larvae were in arrested development before the calves were treated. In calves given doses of 8 mg of levamisole/kg of body weight and 5 and 7.5 mg of fenbendazole/kg, reductions of adult Ostertagia were 95%, 99% and 99%, respectively. Reductions of developing Ostertagia L4 were 29%, 99% and 100%; of arrested Ostertagia L4.sbd.5%, 24% and 72%; of adult Haemonchus.sbd.97%, 100% and 100%; of adult Trichostrongylus.sbd.97%, 99% and 100%, and of adult Cooperia.sbd.100%, 100% and 100%.sbd.as compared with data in untreated controls.

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