A long-lived ascorbate radical in the platinum(II) catalysed reductions of platinum(IV) antitumor drugs
- 1 January 1997
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in J. Chem. Soc., Dalton Trans.
- No. 11,p. 1797-1800
- https://doi.org/10.1039/a700196g
Abstract
A long-lived ascorbate radical was characterized during the reduction of a series of platinum(IV) antitumor drugs; ascorbate reductions proceed through a platinum(IV)–ascorbate intermediate, the formation of which is catalysed by platinum(II).Keywords
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