Present and future of surface plasmon resonance biosensors
Top Cited Papers
- 19 July 2003
- journal article
- review article
- Published by Springer Nature in Analytical and Bioanalytical Chemistry
- Vol. 377 (3) , 528-539
- https://doi.org/10.1007/s00216-003-2101-0
Abstract
Surface plasmon resonance (SPR) biosensors are optical sensors exploiting special electromagnetic waves—surface plasmon-polaritons—to probe interactions between an analyte in solution and a biomolecular recognition element immobilized on the SPR sensor surface. Major application areas include detection of biological analytes and analysis of biomolecular interactions where SPR biosensors provide benefits of label-free real-time analytical technology. This paper reviews fundamentals of SPR affinity biosensors and discusses recent advances in development and applications of SPR biosensors.Keywords
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