Intrapleural administration of a serotype 5 adeno-associated virus coding for α1-antitrypsin mediates persistent, high lung and serum levels of α1-antitrypsin
Open Access
- 31 December 2004
- journal article
- Published by Elsevier in Molecular Therapy
- Vol. 10 (6) , 1003-1010
- https://doi.org/10.1016/j.ymthe.2004.08.022
Abstract
No abstract availableKeywords
This publication has 56 references indexed in Scilit:
- Characterization of Tissue Tropism Determinants of Adeno-Associated Virus Type 1Journal of Virology, 2003
- Improved Hepatic Gene Transfer by Using an Adeno-Associated Virus Serotype 5 VectorJournal of Virology, 2002
- Gene Transfer to the Pleural Mesothelium as a Strategy to Deliver Proteins to the Lung ParenchymaHuman Gene Therapy, 2002
- Stable therapeutic serum levels of human alpha-1 antitrypsin (AAT) after portal vein injection of recombinant adeno-associated virus (rAAV) vectorsGene Therapy, 2001
- Recombinant adeno-associated virus purification using novel methods improves infectious titer and yieldGene Therapy, 1999
- Cell Lines for the Production of Recombinant Adeno-Associated VirusHuman Gene Therapy, 1995
- Adenovirus–mediated in vivo gene transfer and expression in normal rat liverNature Genetics, 1992
- Alpha-1-antitrypsin augmentation therapy for alpha-1-antitrypsin deficiencyThe American Journal of Medicine, 1988
- Molecular basis of alpha-1-antitrypsin deficiencyPublished by Elsevier ,1988
- Replacement Therapy for Alpha1-Antitrypsin Deficiency Associated with EmphysemaNew England Journal of Medicine, 1987