Hormonal Profile and Forearm Metabolism in Human Obesity

Open Access

1 December 1968

journal article
research article
Published by Elsevier in The American Journal of Clinical Nutrition

Vol. 21 (12) , 1438-1444
https://doi.org/10.1093/ajcn/21.12.1438

Abstract

Subjects with simple obesity display hyperinsulinism and blunted HGH responsiveness. Examination of forearm metabolism obese subjects reveals a hormonal pattern compatible with basal hyperinsulinism. Furthermore, there is peripheral resistance to all the actions of insulin that we have examined. Important questions remain regarding the etiology of the insulin resistance associated with, and quantitative fatty acid utilization in, obesity.

Keywords

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