Exclusion of a tight linkage between familial polyposis coli and HLA
- 11 December 2008
- journal article
- research article
- Published by Wiley in Tissue Antigens
- Vol. 22 (5) , 354-358
- https://doi.org/10.1111/j.1399-0039.1983.tb02265.x
Abstract
Linkage was investigated between a dominant gene determining familial polyposis coli (FPC) and HLA in a large pedigree. A tight linkage was excluded at a value of the recombination fraction between 0 and 5%. Linkage studies with various markers should be pursued to permit detection of high risk individuals and to better understand the phenotypic variability observed in certain polyposis families.This publication has 10 references indexed in Scilit:
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