High striatal occupancy of D2-like dopamine receptors by amisulpride in the brain of patients with schizophrenia

Open Access

1 January 1999

journal article
Published by Oxford University Press (OUP) in International Journal of Neuropsychopharmacology

Vol. 7 (4) , 421-430
https://doi.org/10.1017/s1461145704004353

Abstract

The ‘atypicality’ of the antipsychotic drug, amisulpride, has been attributed to preferential extrastriatal binding. Previous investigations of striat

Keywords

DOPAMINE RECEPTORS
SCHIZOPHRENIA
BRAIN
AMISULPRIDE
PLASMA DRUG CONCENTRATION
PUTAMEN
ANTIPSYCHOTIC AGENTS

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