Mitochondrial acetyl-CoA carboxylase. Time course of mobilization/activation in liver of refed rats

Publisher Website
Google Scholar
Abstract
Fated (48 h) rats were killed at 0, 2, 4, 6, 8, 12, 16, 20 and 24 h after they were refed on a high carbohydrate diet. An increase in the maximal activity and quantify of cystolic acetyl-CoA carboxylase was found in liver of refed rats after a lag time of about 8 h. The increased quantity of cytosolic enzyme was attributable primarily to mobilization of mitochondrial storage forms and not to a substantial increase in the rate of synthesis of acetyl-CoA carboxylase.