INVESTIGATIONS ON THE NORMAL EXCRETION OF CORTICOIDS IN THE URINE OF MAN AND THE RELATION OF THE CORTICOIDS TO THE 17-KETOSTEROIDS

Publisher Website
Google Scholar
Abstract
The 24-hr. urinary neutral reducing lipids "corticoids" and 17-ketosteroids were studied in 214 women aged 2-83 yrs., and in 187 men aged 2-80 yrs. Corticoid excretion is slightly higher in males than females at each age. The mean excretion rises from a low level in childhood to a plateau in maturity. Corticoid excretion, expressed in terms of mg./day/sq.m. body surface, is constant from infancy to old age. 17-ketosteroids are excreted in insignificant quantities until puberty; thereafter they rise to a peak, and decline gradually as old age progresses. There is no relationship to body weight or surface area, nor is the 17-ketosteroid excretion related quantitatively to the excretion of corticoids.