Pyrrole chemistry. XXVI. A synthesis of porphobilinogen from pyrrole
- 1 October 1983
- journal article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 61 (10) , 2415-2422
- https://doi.org/10.1139/v83-417
Abstract
A synthetic strategy has been developed which enables pyrrole to be used as the starting material for the synthesis of 2,3,4-trisubstituted pyrroles of the type used to construct porphyrins. The total synthesis of porphobilinogen has been accomplished as a demonstration of the applicability of the approach.Keywords
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