Abstract
The CASP community-wide assessment of protein structure prediction methods (CASP6, 2004, http://predictioncenter.llnl.gov/casp6/) anniversary coincides with a general realization of the need to speed progress, and achieve sustained success in protein structure prediction [see the NIGMS-NIH new initiative for improving protein structure prediction methods (http://www.nigms.nih.gov/)], toward which CASP has substantially contributed. Unfortunately, so far progress has not been as continuous as in other fields of technology, perhaps indicating that substantial new scientific contribu- tions are still required.

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