An examination of the extent of diasterofacial selection in the reactions of a chiral nitrile oxide with achiral alkenes: a route to β-hydroxy carboxylic acids
- 1 January 1983
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 23,p. 1460-1462
- https://doi.org/10.1039/c39830001460
Abstract
A new synthesis of optically active β-hydroxy carboxylic acids has been developed which is based on the (modest) diastereoselective addition of the chiral nitrile oxide (4) to 1,2-disubstituted alkenes.Keywords
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