• 1 January 1976
    • journal article
    • research article
    • Vol. 66  (6) , 546-553
Abstract
Abnormal pancreatic secretory patterns were observed in 17 of 23 patients with Sjogren''s syndrome and in 19 of 31 patients with scleroderma. Pancreatic insufficiency was often associated with depressed gastric secretion and/or abnormal gallbladder function. While in both disorders digestive complaints were attributable to 1 or more dysfunctions, the pathogenetic factors in scleroderma appeared to be more varied and required careful investigation for complete elucidation. Antibiotics, antimetabolites and steroid therapies were additional causal factors involved in the initiation of gastrointestinal dysfunction and pathology.

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