Properties of Leukocyte Catalase in Swiss Type Acatalasemia: A Comparative Study of Normals, Heterozygotes and Homozygotes

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Abstract
Properties of leukocyte catalase from individuals heterozygous and homozygous for Swiss type acatalasemia were found to differ from those of the normal enzyme as well as interindividually in regard to heat stability and electrophoretic mobility. Molecular hybridization is discussed as a possible explanation for the presence of intermediate catalase species. Antigenic identity of catalase from all sources is confirmed.

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