Multiple GPCR conformations and signalling pathways: implications for antagonist affinity estimates
Open Access
- 1 August 2007
- journal article
- review article
- Published by Elsevier in Trends in Pharmacological Sciences
- Vol. 28 (8) , 374-381
- https://doi.org/10.1016/j.tips.2007.06.011
Abstract
No abstract availableKeywords
This publication has 58 references indexed in Scilit:
- A Comparison of the Antagonist Affinities for the Gi- and Gs-Coupled States of the Human Adenosine A1-ReceptorThe Journal of Pharmacology and Experimental Therapeutics, 2007
- Distinct Signaling Profiles of β1 and β2 Adrenergic Receptor Ligands toward Adenylyl Cyclase and Mitogen-Activated Protein Kinase Reveals the Pluridimensionality of EfficacyMolecular Pharmacology, 2006
- Evidence for a Secondary State of the Human β3-AdrenoceptorMolecular Pharmacology, 2005
- The CCR5 Receptor-Based Mechanism of Action of 873140, a Potent Allosteric Noncompetitive HIV Entry InhibitorMolecular Pharmacology, 2005
- Evidence for Pleiotropic Signaling at the Mouse β3-Adrenoceptor Revealed by SR59230A [3-(2-Ethylphenoxy)-1-[(1,S)-1,2,3,4-tetrahydronapth-1-ylamino]-2 S-2-propanol Oxalate]The Journal of Pharmacology and Experimental Therapeutics, 2005
- The selectivity of β‐adrenoceptor antagonists at the human β1, β2 and β3 adrenoceptorsBritish Journal of Pharmacology, 2005
- Coupling of the human A1 adenosine receptor to different heterotrimeric G proteins: evidence for agonist‐specific G protein activationBritish Journal of Pharmacology, 2004
- Allosteric modulation of G protein-coupled receptors: perspectives and recent developmentsDrug Discovery Today, 2004
- Allosteric Modulators: The New Generation of Receptor AntagonistMolecular Interventions, 2004
- Anomalous Behavior of CGP 12177A ON β2-Adrenergic ReceptorsJournal of Receptors and Signal Transduction, 1996