Feedback Loops Shape Cellular Signals in Space and Time
- 17 October 2008
- journal article
- review article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 322 (5900) , 390-395
- https://doi.org/10.1126/science.1160617
Abstract
Positive and negative feedback loops are common regulatory elements in biological signaling systems. We discuss core feedback motifs that have distinct roles in shaping signaling responses in space and time. We also discuss approaches to experimentally investigate feedback loops in signaling systems.Keywords
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