Inhibition by antihistamines of the vascular permeability increase induced by bradykinin

Open Access

1 October 1968

journal article
Published by Wiley in British Journal of Pharmacology

Vol. 34 (2) , 330-336
https://doi.org/10.1111/j.1476-5381.1968.tb07054.x

Abstract

1 Mepyramine and triprolidine hydrochloride have a marked inhibitory effect on the local increase of vascular permeability induced by bradykinin. 2 The anti‐bradykinin effect of both antihistamines was species dependent, being evident in rabbits, rats and mice but not in guinea‐pigs.

Keywords

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