Measurement of cardiac output by earpiece dye-dilution method with automatic calibration of dye concentration.
- 1 January 1977
- journal article
- research article
- Published by Tohoku University Medical Press in The Tohoku Journal of Experimental Medicine
- Vol. 122 (1) , 51-58
- https://doi.org/10.1620/tjem.122.51
Abstract
A non-invasive method for measuring cardiac output by an earpiece dye densitometer was proposed. The densitometer is dichromatic and has an air capsule to make subject''s ear bloodless by inflation, so that it can calibrate indocyanine green dye concentration without blood sampling. Duplicate measurements of cardiac output showed a good agreement in 40 cases (r = 0.97, SD = 8.9%), which was comparable to the result of the cuvette method (r = 0.98, SD = 8.1%). Simultaneous measurements of cardiac output by the earpiece method (x) and the standard cuvette method (y) revealed a good agreement (r = 0.91, y = 0.96x + 0.34, SD = 16.4%) in 52 measurements of 25 cases. A good correlation was obtained between the 2 methods during ergometer exercise in the supine position in 5 cases. This earpiece dye-dilution method is probably reliable for cardiac output measurement and advantageous for clinical use because of the non-invasive technique.Keywords
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