The Relationship of Cardiovascular Disease to Hyperglycemia

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Abstract
In an epidemiologic study of a total natural community, Tecumseh, Michigan, 87 known adult diabetics, 33 men and 54 women, were identified from the examined population of 5,140 persons 16 years of age or older. These persons had a higher prevalence of vascular disease than the nondiabetic persons of similar age and sex. Conversely, among participants with each of 5 manifestations of vascular disease, coronary heart disease, other vascular disease (cerebral or peripheral vascular disease), T wave inversion in the electrocardiogram, systolic hypertension or diastolic hypertension, the proportion with elevated blood glucose levels was significantly greater than among persons of the same sex and age group in the total examined population. A high prevalence of hyperglycemia has not been reported among persons with vascular disease in any previous epidemiological study. The significance of this finding is discussed.