Plateletpheresis Residues: A Source of Large Quantities of Human Blood Lymphocytes

Abstract
The residue from single-donor plateletpheresis contains a large number of human mononuclear cells. More than 1 .times. 109 viable lymphocytes were harvested for laboratory study from the leukocyte-rich sediment that was previously discarded. Prior to removal by adherence, 5 .times. 108 monocytes were also available for further purification, if desired. The physical properties and response to phytohemagglutinin were very similar when lymphocytes isolated from plateletpheresis residues were compared with those obtained directly from venous blood.