CYCLIC-NUCLEOTIDES VARY BY AREA IN THE RETINA AND PIGMENTED EPITHELIUM OF THE HUMAN AND MONKEY
- 1 January 1980
- journal article
- research article
- Vol. 19 (8) , 864-869
Abstract
Cyclic[c]GMP and cAMP are present in lower concentrations in the central (macular) region of the neural retina of the human and monkey than in other areas. This pattern approximates the distribution of rod photoreceptor cells. Surprisingly, an inverse gradient of cGMP concentration is observed in the pigmented epithelium. Levels in the central region are over 4-fold higher than in cells in the periphery, offering the 1st evidence of biochemical differences in this embryologically uniform cell type.This publication has 8 references indexed in Scilit:
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