NEONATAL THYMUS GRAFTS .1. STUDIES ON THE REGULATION OF THE LEVEL OF CIRCULATING THYMIC FACTOR (FTS)
- 1 January 1979
- journal article
- research article
- Vol. 36 (2) , 207-213
Abstract
The level of FTS, tested by its action on spleen rosette-forming cells from adult thymectomized mice, was stable in young animals. This stability suggests a regulatory mechanism. The FTS level was disrupted by neonatal thymus grafting in adult normal and thymectomized animals or by injections of synthetic thymic factor into normal, thymectomized mice, grafted or ungrafted. After an initial increase over the normal value, FTS levels returned close to the previous range, indicating the existence of some homeostatic mechanism of FTS secretion.This publication has 14 references indexed in Scilit:
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