Unsuspected Cirrhosis Discovered During Elective Obesity Operations
Open Access
- 1 January 1998
- journal article
- review article
- Published by American Medical Association (AMA) in Archives of Surgery
- Vol. 133 (1) , 84-88
- https://doi.org/10.1001/archsurg.133.1.84
Abstract
IN THE 1960s and 1970s, a liver biopsy was routinely performed in conjunction with jejunoileal bypass operations performed for the treatment of morbid obesity. The histologic incidence of fatty liver in those patients ranged from 60% to 90%.1-3 In the same reports, a few patients were found to have more advanced stages of liver disease characterized by infiltration with inflammatory cells, Mallory bodies, centrolobular necrosis, and fibrosis. These reports provide the first evidence of the possible association between severe obesity and cirrhosis.Keywords
This publication has 7 references indexed in Scilit:
- Nonalcoholic steatohepatitis: An expanded clinical entityGastroenterology, 1994
- The Natural History of Nonalcoholic Steatohepatitis: A Follow–Up Study of Forty–Two Patients for Up to 21 YearsHepatology, 1990
- Liver Histology Abnormalities in the Morbidly ObeseHepatology, 1989
- Improving Survival in Patients With Cirrhosis Undergoing Major Abdominal OperationsArchives of Surgery, 1987
- Intra-abdominal Surgery in Patients With Advanced CirrhosisArchives of Surgery, 1986
- Clarification of Risk Factors for Abdominal Operations in Patients with Hepatic CirrhosisAnnals of Surgery, 1984
- Late hepatic histopathology after jejunoileal bypass for morbid obesityThe American Journal of Surgery, 1981