X-mapping in man: evidence against measurable linkage between anhidrotic ectodermal dysplasia and G6PD deficiency.
Open Access
- 1 June 1979
- journal article
- case report
- Published by BMJ in Journal of Medical Genetics
- Vol. 16 (3) , 223-224
- https://doi.org/10.1136/jmg.16.3.223
Abstract
A Sardinian kindred segregating for X-linked anhidrotic ectodermal dysplasia (AED), glucose-6-phosphate dehydrogenase (G6PD) deficiency of Mediterranean type, and Xga blood antigen provides evidence against a measurable linkage between the loci for AED and G6PD. Moreover, from the segregation of the combined phenotypes in four scorable sons from two triple heterozygotes with phase known, it seems highly probable that the AED locus is nearer to the centromere than is the G6PD locus.Keywords
This publication has 6 references indexed in Scilit:
- VARIABILITY OF RED-CELL PHENOTYPES BETWEEN AND WITHIN INDIVIDUALS IN AN UNBIASED SAMPLE OF 77 HETEROZYGOTES FOR G6PD DEFICIENCY IN SARDINIA1976
- Report of the committee on the genetic constitution of the X and Y chromosomes.1976
- X Chromosome Inactivation in X-linked Hypohidrotic Ectodermal DysplasiaNature New Biology, 1973
- Failure to detect linkage between Xg and other X‐borne loci in SardiniansAnnals of Human Genetics, 1966
- STUDIES OF GLUCOSE-6-PHOSPHATE DEHYDROGENASE ACTIVITY OF INDIVIDUAL ERYTHROCYTES - METHEMOGLOBIN-ELUTION TEST FOR IDENTICATION OF FEMALES HETEROZYGOUS FOR G6PD DEFICIENTY1965
- Blood Groups in ManPopulation, 1951