MOLECULAR MAKEUP OF HIV-1 ENVELOPE PROTEIN

1 January 2004

journal article
review article
Published by Taylor & Francis in International Reviews of Immunology

Vol. 23 (5-6) , 383-411
https://doi.org/10.1080/08830180490432749

Abstract

A broad range of structural, functional, and immunological similarities between HIV-1 gp120 and human proteins, especially those participating in immune responses, highlight gp120 as a pleiotropic protein that can in different ways affect many important functions of the human immune system. Here we described some of these properties of HIV-1 gp120 that represent the main obstacle in the development of effective and safe AIDS vaccine.

Keywords

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