Biosynthesis of Mikrolin
- 20 September 1978
- journal article
- research article
- Published by Wiley in Helvetica Chimica Acta
- Vol. 61 (6) , 2002-2018
- https://doi.org/10.1002/hlca.19780610609
Abstract
Mikrolin (8) and dechloromikrolin (9) have been shown to exist as tautomeric mixtures in solution. The structures of mono‐O‐trifluoroacetyl Mikrolin (10) and di‐O‐acetyl Mikrolin (11) have been elucidated. The products 15 to 23 from reduction of the metabolites 8 9 with Pd/C and Zn in aqueous acetic acid have been identified. The 13C‐NMR. spectra of Mikrolin (8) and dechloromikrolin (9) and their derivatives have been completely assigned Based on the results of incorporation experiments with sodium [1‐13C]‐, [2‐13C]‐ and [1, 2‐13C]‐acetate, a biosynthetic pathway is proposed for Mikrolin (8).This publication has 7 references indexed in Scilit:
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