Synthesis of 4-substituted tetronic acids: multicolanic acid
- 1 January 1979
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 2,p. 81-82
- https://doi.org/10.1039/c39790000081
Abstract
Multicolanic acid (3), and other 4-substituted tetronic acids (8), (9), (10), and (17) are conveniently synthesised from the corresponding unsubstituted parent compounds by protection of the enolic hydroxy-groups with pyrrolidine, and reaction of the carbanions of the resultant derivatives with either alkyl halides or aldehydes, followed by acid catalysed removal of the protecting groups.This publication has 1 reference indexed in Scilit:
- Total synthesis and stereostructure of methyl (E)-O-methylmulticolanate, a 4-ylidenetetronic acid from Penicillium multicolorJournal of the Chemical Society, Chemical Communications, 1978