Energy Wastage in Rats Given Drugs That Induce Microsomal Enzymes
- 1 December 1975
- journal article
- research article
- Published by Elsevier in Journal of Nutrition
- Vol. 105 (12) , 1544-1548
- https://doi.org/10.1093/jn/105.12.1544
Abstract
Metabolic efficiency was studied in rats given drugs known to induce hepatic microsomal enzymes. The presence of an increased metabolic rate was indicated by increases in oxygen consumption under various experimental conditions and by changes in body weight. The latter was not accounted for by increased losses of energy in excreta. The results support the hypothesis that hepatic microsomal enzyme induction can significantly alter the body's metabolic efficiency.Keywords
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