A dynamic empirical model of the human response to sodium nitroprusside during cardiac surgery
- 1 January 1988
- conference paper
- Published by Institute of Electrical and Electronics Engineers (IEEE)
Abstract
A description is given of a partially successful attempt at using real operating room data to generate a dynamic model of the human response to sodium nitroprusside (SNP) during cardiac surgery. The principal goal of the model is to understand the problems associated with adaptive closed loop control of blood pressure during such surgeries. If successful, such a model would be valuable for simulating patients while designing controllers and would also be useful in the construction of estimation algorithms for use in adaptive controllers. The model presented dynamically relates mean arterial pressure (MAP) as a function of SNP infusion and unmeasured disturbances. It uses data (0.5-Hz sampling rate) on MAP and SNP taken over a complete cardiac surgery. Special attention is given to modeling the noise characteristics of the MAP signal.Keywords
This publication has 3 references indexed in Scilit:
- Engineering implications of closed-loop control during cardiac surgeryJournal of Clinical Monitoring and Computing, 1990
- Self-tuning controller for drug delivery systemsInternational Journal of Control, 1988
- An efficient AI based algorithm for validating pulsatile arterial pressure waveformsPublished by Institute of Electrical and Electronics Engineers (IEEE) ,1988