Effect of Staphylococcal Toxin on Renal Function

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Abstract
The effect of varying intravenous doses of a staphylococcal toxin on renal function has been studied. Results indicate that the toxin in low doses acts selectively on the kidney. Both total and estimated renal blood flow and glomerular filtration were decreased by doses of toxin insufficient to cause significant systemic blood pressure changes or pathologic alterations in other organ systems.