Haemoglobin Belfast 15 (A12) Tryptophan->Arginine: A New Unstable Haemoglobin Variant
- 9 November 1974
- Vol. 4 (5940) , 324-326
- https://doi.org/10.1136/bmj.4.5940.324
Abstract
A new unstable haemoglobin, α2β215 Trp→ Arg (Hb Belfast), with increased oxygen affinity has been found during the routine investigation of a long-stay psychiatric patient. It seemed to cause little haematological disorder. The reticulocytes synthesized normal and abnormal β-chains at the same rate but in the circulating blood Hb Belfast amounted to only 27·5% of the total haemoglobin.Keywords
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