Abstract
Embryonic hearts transplanted from A. tigrinum to A. punctatum (a smaller species) became of larger size than the organ of the controls of either species, and when the reciprocal graft was made the organ became abnormally small, in agreement with results of heteroplastic limb experiments of Harrison (1924). By the time of metamorphosis a certain amount of regulation had occurred, bringing the abnormally large heart to more nearly normal size. The pulsation rate of grafted hearts was always much nearer the rate of the controls of the donor than of the host species.

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