The inhibition by p-aminobenzoic acid of the development of paludrine-resistance as produced by sulphonamides in plasmodium gallinaceum

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Abstract
A strain of Plasmodium gallinaceum has been treated for 10 weeks with sulphadiazine (5 mg./20 g.) in the presence of p-aminobenzoic acid in doses (0·5 mg./ 20 g.) inhibiting the sulphadiazine. No resistance to paludrine or to sulphadiazine has developed.