Regional ileitis, ulcerative colitis, and clubbed fingers

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Abstract
Summary In a retrospective study of patients with regional ileitis or ulcerative colitis, it was found that 23 of a total of 68 patients with the histologic diagnosis of regional ileitis, confined to the area of the gut supplied by the vagus nerve, had clubbed fingers. The marked fibrosis in regiona ileitis may well be a factor in the reflex mechanism responsible for clubbing of the fingers. By contrast, only three patients of a total of 77 with the histologic diagnosis of ulcerative colitis had clubbed fingers, and two of these patients had associated hepatic cirrhosis.