Comparison of Serum C-Reactive Protein, Glycoprotein and Seromucoid in Cancer, Arthritis, Tuberculosis and Pregnancy.

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Abstract
Parallel determinations of C-reactive protein, glycoprotein and seromucoid were made on the sera from patients with cancer, arthritis, and tuberculosis and on the sera of pregnant subjects. C-reactive protein was found to be present in most cases of carcinoma as well as in inflammatory states. In cancer, acute rheumatoid arthritis, and active tuberculosis, CRP is significantly correlated with seromucoid and with glycoprotein. In pregnancy, which is characteristically accompanied by elevated serum glycoprotein and normal seromucoid levels, CRP is only occasionally found. This suggests that the elevated serum glycoprotein found in pregnancy may be due to causes other than inflammation.