Spontaneous Impulse Activity of Rat Retinal Ganglion Cells in Prenatal Life
- 7 October 1988
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 242 (4875) , 90-91
- https://doi.org/10.1126/science.3175637
Abstract
The existence of spontaneous neural activity in mammalian retinal ganglion cells during prenatal life has long been suspected. This activity could play a key role in the refinement of retinal projections during development. Recordings in vivo from the retinas of rat fetuses between embryonic day 17 and 21 found action potentials in spontaneously active ganglion cells at all the ages studied.This publication has 9 references indexed in Scilit:
- Prenatal Tetrodotoxin Infusion Blocks Segregation of Retinogeniculate AfferentsScience, 1988
- The influence of neuronal activity on patterns of synaptic connectionsTrends in Neurosciences, 1987
- Spontaneous and evoked activity of fetal primary afferents in vivoNature, 1987
- Topographic targeting errors in the retinocollicular projection and their elimination by selective ganglion cell deathJournal of Neuroscience, 1986
- Binocular impulse blockade prevents the formation of ocular dominance columns in cat visual cortexJournal of Neuroscience, 1986
- A role for action-potential activity in the development of neuronal connections in the kitten retinogeniculate pathwayJournal of Neuroscience, 1986
- Changes in the numbers of optic nerve fibers during late prenatal and postnatal development in the albino ratDevelopmental Brain Research, 1985
- Prenatal development of functional connections in the cat's retinogeniculate pathwayJournal of Neuroscience, 1984
- Prenatal development of the optic projection in albino and hooded ratsDevelopmental Brain Research, 1983