Peptide histidine isoleucine (PHI)
- 1 October 1983
- journal article
- research article
- Published by Springer Nature in Digestive Diseases and Sciences
- Vol. 28 (10) , 893-896
- https://doi.org/10.1007/bf01317039
Abstract
PHI (peptide histidine isoleucine) is a recently identified porcine peptide, present in large quantities in the intestine, which has sequence homologies with VIP, an established intestinal secretagogue, and with secretin, glucagon, and GIP. The effects of PHI on jejunal, ileal, and colonic fluid and electrolyte transport were studied in the pig. PHI appears to be an intestinal secretagogue inducing a reversible net secretion of fluid and electrolytes in jejunum and ileum and less marked effects in the colon.This publication has 13 references indexed in Scilit:
- Radioimmunoassay and intramural distribution of PHI-IR in human intestineDigestive Diseases and Sciences, 1983
- ARE PEPTIDE HISTIDINE ISOLEUCINE AND VASOACTIVE INTESTINAL PEPTIDE CO-SYNTHESISED IN THE SAME PRO-HORMONE?The Lancet, 1982
- Vascular effects of the peptides PYY and PHI: Comparison with APP and VIPEuropean Journal of Pharmacology, 1982
- Actions of a newly isolated intestinal peptide PHI on pancreatic aciniAmerican Journal of Physiology-Gastrointestinal and Liver Physiology, 1981
- Isolation and characterization of the intestinal peptide porcine PHI (PHI-27), a new member of the glucagon--secretin family.Proceedings of the National Academy of Sciences, 1981
- Actions of a new peptide from porcine intestine (PHI) on pancreatic secretion in the rat and turkeyLife Sciences, 1980
- Porcine peptide having N‐terminal histidine and C‐terminal isoleucine amide (PHI)FEBS Letters, 1980
- Isolation of two novel candidate hormones using a chemical method for finding naturally occurring polypeptidesNature, 1980
- Effect of VIP infusion on water and ion transport in the human jejunumGastroenterology, 1980
- Experimental evidence for vasoactive intestinal peptide as the cause of the watery diarrhea syndromeGastroenterology, 1978