K-Cell Activity in Aplastic Anaemia

Abstract
K[killer]-cell activity was measured by specific cytotoxicity and cytotoxic capacity in 29 patients with aplastic anemia. Nine patients had a reduction of the specific cytotoxicity and 12 had a decreased cytotoxic capacity. The decreased cytotoxic capacity correlates with the severity of aplastic anemia. Some of the possible causes of the reduction of this activity were investigated.