Gamma Knife Radiosurgery for Acoustic Schwannoma: Effects of Low Radiation Dose and Functional Prognosis
- 1 January 1996
- journal article
- clinical trial
- Published by S. Karger AG in Stereotactic and Functional Neurosurgery
- Vol. 66 (1) , 134-141
- https://doi.org/10.1159/000099803
Abstract
The effects of relatively low dose Gamma Knife irradiation on acoustic schwannoma were evaluated in 29 patients followed over 2 years after treatment. The mean dose delivered to the tumor periphery was 12.1 Gy. Lowering of the magnetic resonance signal intensity in the tumor center appeared in 69% and signs of tumor shrinkage appeared in 59% of cases. The cyst in the tumor enlarged in 3 cases, and 2 cases developed hydrocephalus. The percentage of pure-tone hearing preservation was 82% at 3 months, 73% at 6 months, 68% at 12 months, 64% at 18 months and 59% at 24 months in 22 out of 29 cases. Relatively low dose Gamma Knife radiosurgery was effective in suppressing tumor growth, with preservation of hearing.Keywords
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