The structure of acetomycin. Spectroscopic characterization and X-ray analysis of a bromo derivative.
- 1 January 1985
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 38 (12) , 1684-1690
- https://doi.org/10.7164/antibiotics.38.1684
Abstract
Acetomycin (1a), known since 1958, has been further characterized by NMR and CD spectra. The 3-acetyl side chain of 1a is reduced selectively by sodium cyanoborohydride yielding the diastereomeric alcohols 2a and 3a, which were esterified to the crystalline bromoacetates 2c and 3c. The structure and absolute configuration of 3c was determined by X-ray analysis. From these data the absolute configuration of 1a followed as 3S, 4S, 5R.This publication has 3 references indexed in Scilit:
- Stoffwechselprodukte von Actinomyceten. 39. Mitteilung. Zur Biogenese des AcetomycinsHelvetica Chimica Acta, 1963
- Stoffwechselprodukte von Actinomyceten. 12. Mitteilung. Über die Isolierung und Charakterisierung von AcetomycinHelvetica Chimica Acta, 1958
- Stoffwechselprodukte von Actinomyceten. 13. Mitteilung. Über die Konstitution von AcetomycinHelvetica Chimica Acta, 1958