Variability ofAspergillus niger after treatment withN-methyl-N′-nitro-N-nitrosoguanidine

1 March 1978

journal article
research article
Published by Springer Nature in Folia Microbiologica

Vol. 23 (2) , 103-107
https://doi.org/10.1007/bf02915309

Abstract

N-Methyl-N′-nitro-N-nitrosoguanidine influences strongly the variability ofAspergillus niger MU 90, particularly on long-term treatment. The number of spores capable of growth decreases with the duration of treatment and the number of morphological and biochemical mutants considerably increases. The highest number of mutants with increased organic acid production was obtained after a mutagenic treatment when the number of surviving spores decreased below 1%.

Keywords

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