Successful Treatment of Extensive Posttraumatic Soft-Tissue and Renal Infections Due to Apophysomyces elegans

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Abstract
We describe the clinical course and successful treatment of a previously healthy man who, after experiencing trauma, presented with severe cutaneous mucormycosis due to Apophysomyces elegans and subsequently developed secondary renal infection. A multidisciplinary approach employing aggressive surgical debridement and therapy with hyperbaric oxygen, liposomal amphotericin B, and interferon-γ was successful in controlling his infection, obviating the need for nephrectomy.

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