THE ETIOLOGY OF BANTI'S SYNDROME; FURTHER SUPPORT OF THE "CONGESTIVE SPLENOMEGALY" HYPOTHESIS

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Abstract
A case of Banti''s syndrome is reported in which the pathogenetic lesion was a congenital obstruction of the portal vein at its termination within the liver. The patient was a 33 yr. old white 9 who was well until the age of 25. At operation, one yr. prior to her death, the liver appeared normal and the spleen, weighing 550 gs., was removed. She died of recurrence of massive hematemasis. Autopsy revealed a normal liver but an almost blind-end termination of the portal vein at its entrance into the liver. There was dilatation of the portal system and extensive collateral circulation between the portal and systemic venous circuits. A perforation of the mucosa of the stomach communicated with a large varix and was the source of the fatal hemorrhage.

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